The enolate of an ester can be treated with a ketone to
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The enolate of an ester can be treated with a ketone to give a ?-hydroxy ester. Draw a mechanism for this aldol-like rea
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The enolate of an ester can be treated with a ketone to give a ?-hydroxy ester. Draw a mechanism for this aldol-like reaction. The ? position of the nitrile is first deprotonated to give a resonance-stabilized anion (like an enolate), which then functions as a nucleophile to attack the alkyl halide. (a) Draw the mechanism for this process. (b) Using this process, show the reagents you would use to achieve the following transformation:
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