A porous polyurethane rubber arterial prosthesis was imp
Question and Solution
A porous polyurethane rubber arterial prosthesis was implanted in dogs, and it was found that half pores were filled wit
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A porous polyurethane rubber arterial prosthesis was implanted in dogs, and it was found that half pores were filled with tissue after 3 months of implantation. The prosthesis had a 5-mm inside diameter and was 1 mm thick, 10 cm long, and had a porosity of 30%. a. Calculate the wall tension assuming a (high) blood pressure of 200 mm Hg immediately after implantation: T = P q r; 133.3 Pa = 1 mm Hg. b. Calculate the maximum force (N) on the arterial wall developed by the blood pressure (200 mm Hg). c. Calculate the maximum stress (MPa) on the arterial wall developed by the blood pressure (200 mm Hg). d. What is the most important factor related to success of the artificial vascular graft? e. The porous polyurethane rubber graft leaked blood. What would you do to prevent leakage of blood after implantation? f. What is the name of the anticoagulant used to prevent clotting of the prosthesis?
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